Linked Life Data

7104662

Source:http://linkedlifedata.com/resource/pubmed/id/7104662

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1982-10-29
pubmed:abstractText
A large family with Pick's disease was re-examined after twenty years. Five new cases were found, one in the fourth and four in the fifth generation. This family now includes 25 patients with the clinical diagnosis Pick's disease, proven by autopsy in 14, and 7 patients in whom the same diagnosis was considered likely, over six generations. The additional information strongly supports the previously postulated dominant mode of inheritance in this family. In connection with the possible hereditary nature of Pick's disease in general, data on reported families in which the disease occurred in two or more generations and unpublished data on three other families are discussed. Since the diagnosis Pick's disease was certain in affected members of this family, the value of electroencephalography and computerized tomography could be assessed. Persons at risk but without clinical signs of the disease were investigated in the same way, and in 4 cases out of 12, distinct frontal atrophy was found. In one of these cases clinical signs of Picks disease became manifest a year after the investigation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0006-8950
pubmed:author
pubmed:issnType
Print
pubmed:volume
105 (Pt 3)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
443-59
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Hereditary Pick's disease: second re-examination of the large family and discussion of other hereditary cases, with particular reference to electroencephalography, a computerized tomography.
pubmed:publicationType
Journal Article