Linked Life Data

7100691

Source:http://linkedlifedata.com/resource/pubmed/id/7100691

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1982-9-24
pubmed:abstractText
We performed single breath washouts in 14 dogs and 4 pigs using a gas mixture containing 5% helium (He) and 5% sulphur hexafluoride (SF6) with, and without, an end inspiratory breathhold. In dogs, the slope of the alveolar plateau was steeper for SF6 than for He, the difference decreasing after 20 sec of breathholding. In contrast, in pigs there was no difference between the two slopes although both were steeper than in dogs. Following a 15-sec breathhold, both slopes decreased, that of the He plateau becoming significantly flatter than that for SF6. Furthermore, the expirate became relatively SF6 enriched. The results indicate that in pigs the mechanism responsible for the sloping alveolar plateau is not diffusion dependent, and hence cannot be due to 'stratification'. Neither do the results support diffusive interaction within an asymmetrical acinus as a basis for the slope. Our findings suggest that the latter is due to sequential emptying of relatively large units subtended by a branch point in which gas transport is entirely convective.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0034-5687
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-9
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Gas mixing in the lungs of dogs and pigs.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't