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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1977-10-20
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pubmed:abstractText |
Fifty patients with disseminated testicular cancer were treated with a three-drug combination consisting of cis-diamminedichloroplatinum, vinblastine, and bleomycin. Three patients were considered inevaluable due to early death. This chemotherapy regimen produced 74% complete and 26% partial remissions. Furthermore, five patients with partial remission became disease-free after surgical removal of residual disease, producing an overall 85% disease-free status. Toxicity, although significant during remission induction with cis-platinum, vinblastine, and bleomycin, was usually manageable, although there were two drug-related deaths during this period. Thirty-eight of these patients remain alive and 32 remain alive and disease-free at 6 + to 30 + months. We believe this regimen represents a major advance in the management of patients with disseminated testicular cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-4819
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
293-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:71004-Adolescent,
pubmed-meshheading:71004-Adult,
pubmed-meshheading:71004-Bleomycin,
pubmed-meshheading:71004-Cisplatin,
pubmed-meshheading:71004-Drug Therapy, Combination,
pubmed-meshheading:71004-Humans,
pubmed-meshheading:71004-Leukopenia,
pubmed-meshheading:71004-Male,
pubmed-meshheading:71004-Middle Aged,
pubmed-meshheading:71004-Remission, Spontaneous,
pubmed-meshheading:71004-Testicular Neoplasms,
pubmed-meshheading:71004-Uremia,
pubmed-meshheading:71004-Vinblastine
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pubmed:year |
1977
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pubmed:articleTitle |
Cis-diamminedichloroplatinum, vinblastine, and bleomycin combination chemotherapy in disseminated testicular cancer.
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pubmed:publicationType |
Journal Article
|