Linked Life Data

7097819

Source:http://linkedlifedata.com/resource/pubmed/id/7097819

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1982-9-10
pubmed:abstractText
Unanesthetized male Sprague-Dawley rats were bled 40% of their blood volume. After 1 hour of hypovolemia, the animals were resuscitated with either lactated Ringer's solution (LRS) or hypertonic lactated saline (HLS). They received a volume of crystalloid equal to the shed blood volume or twice the shed blood volume. Twenty-four hours after resuscitation, the animals were sacrificed and the brains excised. The per cent water content was determined. Severe hemorrhage without resuscitation resulted in significantly increased intracerebral water content (77.7 +/- 1.0 vs 78.9 +/- 0.7 p less than 0.05). Resuscitation with twice the shed blood volume of either LRS or HLS prevented this increase in intracerebral water. These data support the conclusion that adequate resuscitation is the critical factor in preventing cerebral edema following acute severe hemorrhage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-5282
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
588-90
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Cerebral edema following acute hemorrhage in a murine model: the role crystalloid resuscitation.
pubmed:publicationType
Journal Article