Linked Life Data

7097493

Source:http://linkedlifedata.com/resource/pubmed/id/7097493

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1982-9-10
pubmed:abstractText
In dissolution studies of whole and halved 100-mg sustained-release theophylline tablets, drug release from halved tablets was significantly higher. These differences were not reflected in the bioavailability studies. The area under the curve (AUC) mean absorption time and fraction-of-dose recovered in urine at 24 hr were not significantly different following the ingestion of whole or halved 100-mg tablets. The elimination rate constant, half-life, volume of distribution, plasma, and renal clearance values were consistent with values reported previously. Discrepancies were found in the 24-hr metabolite distribution as compared to literature values and may be accounted for by the age and health of the subjects and the frequency of dosing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-3549
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
505-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Dissolution and bioavailability studies of whole and halved sustained-release theophylline tablets.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't