Linked Life Data

7096625

Source:http://linkedlifedata.com/resource/pubmed/id/7096625

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-9-10
pubmed:abstractText
The development of cytoarchitecture in the lumbar spinal cord of mouse embryo between embryonic day 13 (E13) and E15 was studied by scanning and transmission electron microscopy. A pattern of two perpendicularly oriented sets of cellular elements was found in the intermediate zone at both E13 and E14. One set consisted of radially oriented processes that often originated from cell bodies in the ventricular zone. The second set consisted of cell bodies and processes that were oriented predominantly parallel to the neural tube margin and in the transverse plane. This set was termed circumferential elements and included most of the immature neurons. At E13, the circumferentially oriented cells were arranged into rostrocaudally compressed sheets or layers that were partially segregated one from another by flattened bundles of radially oriented processes. This pattern of orthogonally arranged circumferential and radial elements remained evident through E14 when the profuse growth of cellular processes began of obscure the identity of individual cells seen on the scanned surface. The exposed intermediate zone surface at E14 and E15 often has relatively flat transverse areas separated by ledges of broken tissues, indicating that most neurites grow in the transverse plane. These observations indicate that the sequential patterned development of an organized morphological substratum is an important factor in orienting neurite growth.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0021-9967
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
205
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
360-70
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Guidance of neuritic growth in the transverse plane of embryonic mouse spinal cord.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.