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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1982-9-17
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pubmed:abstractText |
Fourteen previously untreated patients with metastatic nonseminomatous germ-cell cancer of the testis (NSGC) were treated with a modified VAB-4 regimens that was designed to reduce treatment-related morbidity. Nine of ten patients with minimal disease and the only patient with advanced pulmonary disease achieved a complete response (CR) with chemotherapy alone. Two of three partial responders with advanced abdominal disease were converted to CR status with radiotherapy and/or surgery. None of the 12 CRs has had a relapse (median duration of follow-up, 28+ months). We observed no granulocytopenic fever or permanent renal insufficiency. These results indicate that NSGC patients with a low tumor burden can be spared substantial toxicity without the complete response rates being adversely affected.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
668-71
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7093904-Antineoplastic Agents,
pubmed-meshheading:7093904-Drug Administration Schedule,
pubmed-meshheading:7093904-Drug Therapy, Combination,
pubmed-meshheading:7093904-Humans,
pubmed-meshheading:7093904-Leukopenia,
pubmed-meshheading:7093904-Lung Neoplasms,
pubmed-meshheading:7093904-Male,
pubmed-meshheading:7093904-Testicular Neoplasms,
pubmed-meshheading:7093904-Thrombocytopenia
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pubmed:year |
1982
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pubmed:articleTitle |
Nonseminomatous germ-cell cancer of the testis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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