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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1982-9-24
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pubmed:abstractText |
Variation in the activity of superoxide dismutase, glutathione peroxidase (tretbutyl hydroperoxide as a substrate) and glutathione-S-transferase (1-chloro-2,4-dinitrobenzene as a substrate) was studied in rat ischemia and in coronaro-occlusion myocardial infarction. The activity of superoxide dismutase and glutathione peroxidase drastically reduced 2-15 minutes after ligation of the coronary artery and remained at the decreased level during the observation period (14 days). The activity of glutathione-S-transferase in the infarcted zone of the myocardium significantly decreased only by day 3 of the experiment. The activity of glutathione peroxidase in the blood of patients with acute myocardial infarction rose more than 1.5-fold.
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pubmed:language |
rus
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0365-9615
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
58-60
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pubmed:dateRevised |
2008-10-8
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pubmed:meshHeading |
pubmed-meshheading:7093510-Animals,
pubmed-meshheading:7093510-Coronary Disease,
pubmed-meshheading:7093510-Glutathione Peroxidase,
pubmed-meshheading:7093510-Glutathione Transferase,
pubmed-meshheading:7093510-Humans,
pubmed-meshheading:7093510-Lipid Peroxides,
pubmed-meshheading:7093510-Male,
pubmed-meshheading:7093510-Middle Aged,
pubmed-meshheading:7093510-Myocardial Infarction,
pubmed-meshheading:7093510-Myocardium,
pubmed-meshheading:7093510-Oxygen Consumption,
pubmed-meshheading:7093510-Peroxidases,
pubmed-meshheading:7093510-Rats,
pubmed-meshheading:7093510-Superoxide Dismutase,
pubmed-meshheading:7093510-Time Factors
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pubmed:year |
1982
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pubmed:articleTitle |
[Enzymes of the detoxication of active forms of oxygen and lipoperoxides in experimental ischemia and myocardial infarct].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
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