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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1982-8-14
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pubmed:abstractText |
A virus with the morphologic and biochemical properties of the family Retroviridae has been isolated from cultured cells explanted from a malignant tumor induced by intradermal inoculation of equine sarcoid cells into a combined immunodeficient Arabian foal. By electron microscopy, intracytoplasmic, extracellular, and budding particles measuring 89 to 120 nm with electron-lucent cores were seen. Virus purified from the medium of cultured cells had a buoyant density of 1.15 g/cm3 in isopycnic sucrose-gradient centrifugation, incorporated radiolabeled uridine but not thymidine, and had constitutive RNA-dependent DNA polymerase which required Mn2+ for optimal endogenous activity.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0002-9645
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
804-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7091844-Animals,
pubmed-meshheading:7091844-Cells, Cultured,
pubmed-meshheading:7091844-Horse Diseases,
pubmed-meshheading:7091844-Horses,
pubmed-meshheading:7091844-Magnesium,
pubmed-meshheading:7091844-Manganese,
pubmed-meshheading:7091844-Microscopy, Electron,
pubmed-meshheading:7091844-Retroviridae,
pubmed-meshheading:7091844-Skin Neoplasms,
pubmed-meshheading:7091844-Uridine
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pubmed:year |
1982
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pubmed:articleTitle |
Isolation of a retrovirus from cultured equine sarcoid tumor cells.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|