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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1982-8-14
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pubmed:abstractText |
The hallucinogen analogue trans-2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine was modified by adding a 3-methyl group, either cis or trans with respect to the amino group. These two isomeric cyclopropyl ring-methylated compounds were then tested for activity in the mouse ear-scratch assay and for a contractile effect in the rat fundus preparation. Neither compound was found to possess appreciable activity when compared to the nonmethylated parent, in either assay.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-2623
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
526-30
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7086838-2,5-Dimethoxy-4-Methylamphetamine,
pubmed-meshheading:7086838-Amphetamines,
pubmed-meshheading:7086838-Animals,
pubmed-meshheading:7086838-Behavior, Animal,
pubmed-meshheading:7086838-Chemical Phenomena,
pubmed-meshheading:7086838-Chemistry,
pubmed-meshheading:7086838-Hallucinogens,
pubmed-meshheading:7086838-Injections, Intraperitoneal,
pubmed-meshheading:7086838-Isomerism,
pubmed-meshheading:7086838-Male,
pubmed-meshheading:7086838-Mice,
pubmed-meshheading:7086838-Muscle, Smooth,
pubmed-meshheading:7086838-Muscle Contraction,
pubmed-meshheading:7086838-Rats,
pubmed-meshheading:7086838-Rats, Inbred Strains,
pubmed-meshheading:7086838-Stomach
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pubmed:year |
1982
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pubmed:articleTitle |
Isomeric cyclopropyl ring-methylated homologues of trans-2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine, an hallucinogen analogue.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
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