Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1982-8-7
|
pubmed:abstractText |
Proteoglycans extracted from rabbit corneal stroma can be separated by ion exchange and gel chromatography into two proteokeratan sulfates (PKS-I, PKS-II) and two proteodermatan sulfates (PDS-I, PDS-II). PKS-I (21% of the total glycosaminoglycans) contains 48% protein, and PKS-II (43% of the total) has 57% protein. In both, the only hexosamine is glucosamine, 7% of which is found in oligosaccharides. There is much more sialic acid in the oligosaccharides of PKS-II than of PKS-I, and the amino acid compositions of the two proteoglycans differ significantly. The keratan sulfates isolated from them by papain digestion are different in size, but both are digested by endo-beta-galactosidase. PDS-I (30% of the total glycosaminoglycans) has 32% protein, and 35% of its uronic acid is iduronic acid. PDS-II (6% of the total) has 42% of its uronic acid as iduronic. In general, the four rabbit proteoglycans resembled those of human and bovine corneal stroma in being smaller and more protein-rich than those of cartilage.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Carbohydrates,
http://linkedlifedata.com/resource/pubmed/chemical/Glycosaminoglycans,
http://linkedlifedata.com/resource/pubmed/chemical/Oligosaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/Papain,
http://linkedlifedata.com/resource/pubmed/chemical/Proteoglycans
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0021-9258
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
25
|
pubmed:volume |
257
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
6965-70
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7085613-Amino Acids,
pubmed-meshheading:7085613-Animals,
pubmed-meshheading:7085613-Carbohydrates,
pubmed-meshheading:7085613-Chromatography, Gel,
pubmed-meshheading:7085613-Chromatography, Ion Exchange,
pubmed-meshheading:7085613-Cornea,
pubmed-meshheading:7085613-Female,
pubmed-meshheading:7085613-Glycosaminoglycans,
pubmed-meshheading:7085613-Male,
pubmed-meshheading:7085613-Oligosaccharides,
pubmed-meshheading:7085613-Papain,
pubmed-meshheading:7085613-Proteoglycans,
pubmed-meshheading:7085613-Rabbits
|
pubmed:year |
1982
|
pubmed:articleTitle |
Proteoglycans of rabbit corneal stroma. Isolation and partial characterization.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|