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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1979-1-24
|
| pubmed:abstractText |
Clarification of the mechanisms of the myocardial depression produced by thiamylal was sought by studying the effect of thiamylal upon the sensitivity of contractile proteins to calcium (Ca2+), by using glycerinated muscle fibres from the canine right ventricle. The dose--response relationship between the concentration of Ca2+ and the force of contraction of the glycerinated cardiac muscle fibres was not shifted from the control curve by the administration of thiamylal 67 microgram ml-1. This result suggests that the changes in the sensitivity of contractile proteins to Ca2+ are not responsible for the depression of myocardial performance produced by thiamylal.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0007-0912
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
50
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
881-4
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:708554-Animals,
pubmed-meshheading:708554-Calcium,
pubmed-meshheading:708554-Depression, Chemical,
pubmed-meshheading:708554-Dogs,
pubmed-meshheading:708554-Dose-Response Relationship, Drug,
pubmed-meshheading:708554-Muscle Proteins,
pubmed-meshheading:708554-Myocardial Contraction,
pubmed-meshheading:708554-Thiamylal
|
| pubmed:year |
1978
|
| pubmed:articleTitle |
Effect of thiamylal on the sensitivity of glycerinated cardiac fibres to calcium.
|
| pubmed:publicationType |
Journal Article
|