Linked Life Data

7085465

Source:http://linkedlifedata.com/resource/pubmed/id/7085465

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1982-8-14
pubmed:abstractText
A 4-year-old Quarter Horse gelding with atrial fibrillation, mitral regurgitation, and signs of bilateral congestive heart failure was initially treated IV with digoxin and furosemide. After parenteral digitalization, a daily maintenance dose of digoxin was administered orally at a rate of 21.7 micrograms/kg of body weight. At this dosage, a steady-state serum digoxin concentration of 2.3 ng/ml was achieved without clinical signs of toxicosis. The furosemide dosage was decreased and eventually discontinued as clinical improvement occurred. Clinical signs of congestive heart failure were controlled and sinus rhythm was intermittently established, but an unfavorable prognosis was given for future athletic work. After 35 days of therapy, cardiac catheterization was performed and the horse was euthanatized. At necropsy there was marked dilatation of all cardiac chambers, mitral valve fibrosis, and left atrial jet lesions. The response of this patient suggested that orally administered digoxin may be useful in the management of congestive heart failure in selected equine patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0003-1488
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
180
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
878-83
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Medical management of congestive heart failure in a horse.
pubmed:publicationType
Journal Article, Case Reports