Linked Life Data

7074359

Source:http://linkedlifedata.com/resource/pubmed/id/7074359

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-7-22
pubmed:abstractText
Individual murine spinal cord neurons were grown in dissociated tissue cultures. Using either one or two conventional intracellular microelectrodes neurons were voltage-clamped and current-voltage (I-V) curves were constructed using command pulses. L-Aspartic acid was then applied and I-V curves repeated in the presence of this excitatory amino acid. L-Aspartic acid induced a region of negative slope conductance (RNSC) in the steady-state I-V relationships of these neurons. Such a RNSC accounts for the apparent reduction of conductance in response to excitatory amino acids and its instability likely contributes to the electrogenesis of bursting in central neurons.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
237
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
248-53
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
L-Aspartic acid induces a region of negative slope conductance in the current-voltage relationship of cultured spinal cord neurons.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't