Linked Life Data

7071743

Source:http://linkedlifedata.com/resource/pubmed/id/7071743

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1982-6-24
pubmed:abstractText
Thirteen adult dogs underwent thoracoabdominal bypass operations with 6 or 10 mm expanded polytetrafluoroethylene (PTFE) grafts 25 to 30 cm long. Eight experimental grafts were seeded with cultured autologous endothelial cells prior to implantation. Five unseeded grafts served as controls. Endothelial cells, derived from external jugular vein segments using 0.1% trypsin and 0.5% collagenase solutions, were cultivated for 14 days prior to seeding. Grafts were studied at 2 and 4 weeks after implantation. Endothelial linings in control grafts were restricted to limited anastomotic pannus ingrowths, never exceeding 10% of the graft surface. Experimental grafts demonstrated an endothelial surface coverage averaging 64% and 91% at 2 and 4 weeks, respectively. Generation of an early lining of endothelium in expanded PTFE grafts is possible in a canine model using cultured autologous cells.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0039-6060
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
550-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Expanded polytetrafluoroethylene vascular prostheses seeded with enzymatically derived and cultured canine endothelial cells.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.