Linked Life Data

7069372

Source:http://linkedlifedata.com/resource/pubmed/id/7069372

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1982-6-21
pubmed:abstractText
We have investigated the activities of alloantisera produced in B6 (C57BL/6) and B6.S strain mice reciprocally immunized with unwashed bone marrow and spleen cell suspensions from their respective Fv-2 congenic partner strains, B6.S and B6. These antisera inhibited the formation of colonies by the late erythrocytic progenitors (CFU-E) in plasma cultures seeded with unwashed bone marrow or spleen cells; washed cells were unaffected. Erythropoietic burst formation by the early progenitors (BFU-E) was not significantly inhibited by the antisera, whether the cells were washed or unwashed. We conclude (a) that the congenic antisera are capable of recognizing alloantigens controlled by alleles of Fv-2 or of a closely linked gene locus on chromosome 9; (b) that these alloantigens are situated on the surface of erythrocytic progenitor cells and can be removed by washing; and (c) that the expression of the alloantigens on these cells is influenced by their stage of differentiation.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
155
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1491-500
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Novel differentiation antigens on late erythrocytic progenitor cells detected by alloantisera made between mouse strains congenic at the Fv-2 locus.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't