Linked Life Data

7067053

Source:http://linkedlifedata.com/resource/pubmed/id/7067053

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-6-14
pubmed:abstractText
Atrial muscle isolated from burned guinea pigs was used to assess myocardial contractile changes associated with thermal injury. Muscle was obtained 16-18 hours after the animals were subjected to sham burn (controls) or to scald burn equivalent to 16% of total body surface area. Isometric contractile tension (CT) and its maximal rate of increase (+dT/dt) were not significantly altered by burn. However, the maximal rate of relaxation (-dT/dt) was uniformly less in muscle from the burned group, and this difference was significant at several time intervals after in vitro contractile responses were elicited. Similarly, -dT/dt responses to increased stimulation frequency (0.1-3.0 Hz) and to increased calcium ion concentration (1.0-10.0 mM) were generally less in the burned group, whereas corresponding CT and +dT/dt responses of the burn and controls groups were not significantly different. Present data indicate that atrial muscle removed from moderately burned guinea pigs exhibits normal contractile capabilities, but may be characterized by impaired relaxation properties.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0092-6213
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-73
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Contractile function of heart muscle from burned guinea pigs.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't