Linked Life Data

7066376

Source:http://linkedlifedata.com/resource/pubmed/id/7066376

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-6-24
pubmed:abstractText
1. The effect of triiodothyronine on the metabolism of palmitate, oleate and erucate in isolated rat hepatocytes was studied. 2. In triiodothyronine-treated rats increased oxidation and decreased triacylglycerol formation from palmitate and oleate was observed. For erucate triiodothyronine caused increased oxidation, but had no significant effect on esterification. 3. Glucagon had no effect on the fatty acid metabolism in hepatocytes from triiodothyronine-treated rats, whereas it stimulated the oxidation in hepatocytes from normal rats. Still, after treatment with triiodothyronine, the oxidation of fatty acids was significantly higher than in glucagon-stimulated normal hepatocytes. 4. In isolated rat liver mitochondria triiodothyronine raised the activity of the outer carnitine palmitoyltransferase (EC 2.3.1.21). The activity of the total carnitine palmitoyltransferase was elevated only slightly in isolated mitochondria from triiodothyronine-treated rats. These effects were similar to those seen in fasted rats. 5. Triiodothyronine had no significant influence on the concentration of long-chain acyl-CoA or alpha-glycerophosphate in isolated rat hepatocytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
711
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
90-100
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The metabolism of fatty acids in hepatocytes isolated from triiodothyronine-treated rats.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't