rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
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pubmed:dateCreated |
1982-6-21
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pubmed:abstractText |
1. The effects of two isoenergetic diets differing only in the values for polyunsaturated: saturated fat (P:S values of 0.2 v. 2.0) were studied in twenty adult human volunteers. 2. A period of 14 d on the high P:S diet failed to produce significant changes in fasting triglyceride levels, though there were individual variations. On the other hand, fasting cholesterol levels dropped by 10% (P less than 0.005). High-density-lipoprotein-cholesterol concentrations were not influenced by changes in the P:S value. 3. Investigations into the mechanism by which changes in the P:S value might affect plasma triglyceride values revealed no consistent effects on very-low-density-lipoprotein kinetics, insulin secretion, insulin sensitivity or free fatty acid concentrations. 4. The results of this study suggest that the largest increase in dietary P:S values that is likely to be obtained on a long-term basis may have only a small effect on plasma triglyceride and cholesterol concentrations.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/Fats, Unsaturated,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, VLDL,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
pubmed:issn |
0007-1145
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
259-66
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7066289-Adult,
pubmed-meshheading:7066289-Aged,
pubmed-meshheading:7066289-Cholesterol,
pubmed-meshheading:7066289-Cholesterol, HDL,
pubmed-meshheading:7066289-Dietary Fats,
pubmed-meshheading:7066289-Dose-Response Relationship, Drug,
pubmed-meshheading:7066289-Fasting,
pubmed-meshheading:7066289-Fats, Unsaturated,
pubmed-meshheading:7066289-Female,
pubmed-meshheading:7066289-Humans,
pubmed-meshheading:7066289-Lipoproteins, HDL,
pubmed-meshheading:7066289-Lipoproteins, VLDL,
pubmed-meshheading:7066289-Male,
pubmed-meshheading:7066289-Middle Aged,
pubmed-meshheading:7066289-Structure-Activity Relationship,
pubmed-meshheading:7066289-Triglycerides
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pubmed:year |
1982
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pubmed:articleTitle |
Effects of moderate increases in dietary polyunsaturated: saturated fat on plasma triglyceride and cholesterol levels in man.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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