Linked Life Data

7065510

Source:http://linkedlifedata.com/resource/pubmed/id/7065510

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-5-21
pubmed:abstractText
We evaluated the usefulness of a protected specimen brush (PSB) in obtaining uncontaminated lower respiratory tract material for bacteriologic examination in a primate model of oleic acid-induced acute diffuse lung injury and naturally occurring "nosocomial pneumonia." The bacterial cause of each pneumonia was established by either an immediate postmortem lung aspirate and/or antemortem blood culture. Bacterial pneumonia occurred in 12 of the 15 animals studied. The PSB cultures were sterile in 11 normal, intubated baboons and in 7 animals with non-pneumonic infiltrates by chest radiography. In each of these instances contamination of the specimen by proximal airway flora was avoided with the PSB. Among 10 baboons with bacteriologically documented pneumonias, the PSB cultures correctly identified the causative pathogen in 7 animals despite the presence of diffuse lung infiltrates radiographically, and multiple pathogenic bacteria in proximal airway secretions. Only 1 of 10 (10%) PSB specimens in these animals was contaminated with a possibly unrelated pathogen. The PSB largely avoided contamination of the culture specimen by proximal airway flora, and therefore should be useful in differentiating bacterial colonization of the airways from pneumonia in the presence of diffuse pulmonary infiltrates.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Bacteriologic diagnosis of nosocomial pneumonia in primates. Usefulness of the protected specimen brush.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.