Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-5-21
pubmed:abstractText
A foundry worker developed dyspnea and a restrictive breathing defect after being exposed to diphenylmethane diisocyanate (MD) at work. His symptoms and lung function impairment subsided a few weeks after he left work. Specific inhalation challenges with the offending agent induced general malaise together with a significant increase in body temperature and leukocyte count as well as a significant decrease in forced vital capacity and transfer factor. Total antibody activity to a MDI human serum albumin (MDI-HSA) conjugate was detected by ammonium sulfate precipitation. Specific IgG antibodies were demonstrated by the enzyme-linked immunoabsorbent (ELISA) technique. Thus, it was found that MDI exposure can cause hypersensitivity pneumonitis and induce the production of specific antibodies.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
113-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Occupational hypersensitivity pneumonitis after exposure to diphenylmethane diisocyanate.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Case Reports