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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1982-5-12
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pubmed:abstractText |
Continuous administration of 0.0625% 1,2-diallylhydrazine dihydrochloride in drinking water for life to 6-week-old randomly bred to Swiss mice induced lung tumors. In comparison with the untreated controls, the lung tumor incidence rose from 25 to 80% in the females and from 26 to 80% in the males. The treatment had no apparent effect on the development of other tumor types. Histopathologically, the lesions were classified as adenomas and adenocarcinomas of the lungs. The work is a continuation of our structure activity inquiry concerning the relative carcinogenic potencies of the dialkyl versus the monoalkyl series of hydrazine analogues.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0030-2414
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
104-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:7063162-Adenocarcinoma,
pubmed-meshheading:7063162-Adenoma,
pubmed-meshheading:7063162-Animals,
pubmed-meshheading:7063162-Carcinogens,
pubmed-meshheading:7063162-Female,
pubmed-meshheading:7063162-Hydrazines,
pubmed-meshheading:7063162-Lung Neoplasms,
pubmed-meshheading:7063162-Male,
pubmed-meshheading:7063162-Mice,
pubmed-meshheading:7063162-Neoplasms, Experimental
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pubmed:year |
1982
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pubmed:articleTitle |
1,2-diallylhydrazine dihydrochloride carcinogenesis in mice.
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pubmed:publicationType |
Journal Article
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