Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1982-5-27
pubmed:abstractText
During a period when certain neonates in our nursery developed necrotizing enterocolitis, we studied stool specimens from a population of symptomatic and asymptomatic patients for the presence of Clostridium difficile and its toxin. The presence of the organism among nursery personnel and in the nursery environment was also evaluated. Results showed that five symptomatic neonates and 17 asymptomatic neonates in a population of 37 patients studied in our neonatal intensive care and intermediate care nurseries had positive stool cultures for C. difficile. Toxin was detected in stool from four of five symptomatic patients and was present at dilutions of greater than 1/125 in stool from six asymptomatic patients who were culture positive for C difficile. The organism was not found in stool samples from any nursery personnel but was recovered from the hand culture of a nursery worker and from the inanimate environment. Although our findings support the notion of nosocomial spread of C difficile, we were unable to clearly implicate the organism as the cause of necrotizing enterocolitis in our nursery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-3476
pubmed:author
pubmed:issnType
Print
pubmed:volume
100
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
435-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The prevalence of Clostridium difficile and toxin in a nursery population: a comparison between patients with necrotizing enterocolitis and an asymptomatic group.
pubmed:publicationType
Journal Article, Comparative Study