Linked Life Data

7057803

Source:http://linkedlifedata.com/resource/pubmed/id/7057803

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-4-12
pubmed:abstractText
Ganglioside-and glycoprotein-bound sialic acid in endplate and non-endplate regions of rat diaphragm muscles were assessed 1-16 days after phrenic nerve transection. Sialic acid in glycoproteins (90% of total) and gangliosides (10% of total) from intact hemidiaphragms was distributed uniformly throughout endplate and nonendplate regions. Afer denervation, the total sialic acid per hemidiaphragm increased (days 1-4) and reached a maximum level (days 8-12) which remained constant (days 12-16). These sialic acid changes reflected increments in gangliosides (40% over control), which occurred simultaneously in endplate and non-endplate regions (days 1-8), and increments in sialoglycoproteins (70%-80% over control), which took place much earlier in endplate (days 1-8) than in nonendplate (days 8-14) regions. The results of this study, together with previous data, favor the hypothesis that maintenance of both sialoglycoproteins and gangliosides depends upon an intact innervation, probably through separate mechanisms involving different neurogenic factors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0148-639X
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Gangliosides and sialoglycoproteins in normal and denervated rat diaphragm muscle.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't