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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1982-10-21
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pubmed:abstractText |
Thirty-seven patients with advanced ovarian cancer were treated in a prospective, randomised trial comparing chlorambucil with a combination of cyclophosphamide and cis-diamminedichloroplatinum (cis DDP). Treatment with the combination was associated with an increased overall response rate (69% versus 23%) (p = 0.04). A response was associated with a longer median survival but no survival advantage was demonstrated for patients who received cyclophosphamide/cis DDP. A larger study is needed to evaluate fully the potential of regimens containing cis DDP in the management of advanced ovarian cancer.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0004-8291
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
245-9
|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7052040-Chlorambucil,
pubmed-meshheading:7052040-Cisplatin,
pubmed-meshheading:7052040-Clinical Trials as Topic,
pubmed-meshheading:7052040-Cyclophosphamide,
pubmed-meshheading:7052040-Drug Therapy, Combination,
pubmed-meshheading:7052040-Female,
pubmed-meshheading:7052040-Humans,
pubmed-meshheading:7052040-Ovarian Neoplasms,
pubmed-meshheading:7052040-Prospective Studies,
pubmed-meshheading:7052040-Random Allocation
|
pubmed:year |
1982
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pubmed:articleTitle |
Advanced ovarian cancer: a prospective randomised trial of chlorambucil versus combined cyclophosphamide and cis-diamminedichloroplatinum.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|