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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1982-10-29
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pubmed:abstractText |
In 1977 we reported our results of an ongoing randomized clinical trial evaluating early or delayed adjuvant chemotherapy utilizing 5-flourouracil, cytoxan and prednisone in premenopausal patients with recurrent or advanced breast cancer. At that time the group receiving early systemic chemotherapy was shown to have an improved progression-free interval and appeared to have a trend toward improved survival. The results of subsequent analysis after over 4 more years of follow-up indicate however, that while early employment of systemic chemotherapy does indeed prolong the progression-free interval, and while this advantage has been maintained, there is no survival advantage shown for either group of patients.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0277-3732
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
355-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7051804-Adult,
pubmed-meshheading:7051804-Antineoplastic Agents,
pubmed-meshheading:7051804-Breast Neoplasms,
pubmed-meshheading:7051804-Castration,
pubmed-meshheading:7051804-Clinical Trials as Topic,
pubmed-meshheading:7051804-Cyclophosphamide,
pubmed-meshheading:7051804-Drug Therapy, Combination,
pubmed-meshheading:7051804-Female,
pubmed-meshheading:7051804-Fluorouracil,
pubmed-meshheading:7051804-Follow-Up Studies,
pubmed-meshheading:7051804-Humans,
pubmed-meshheading:7051804-Middle Aged,
pubmed-meshheading:7051804-Neoplasm Metastasis,
pubmed-meshheading:7051804-Neoplasm Recurrence, Local,
pubmed-meshheading:7051804-Prednisone,
pubmed-meshheading:7051804-Random Allocation
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pubmed:year |
1982
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pubmed:articleTitle |
An evaluation of early or delayed adjuvant chemotherapy in premenopausal patients with advances breast cancer undergoing oophorectomy: a later analysis.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
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