Linked Life Data

7050684

Source:http://linkedlifedata.com/resource/pubmed/id/7050684

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-5
pubmed:dateCreated
1982-10-12
pubmed:abstractText
Earlier, we reported that vitamin A (retinol), in vitro, exhibits a strong inhibitory effect on the mutagenicity of aflatoxin B1 in the Ames Salmonella/microsome test. This paper reports the same inhibitory effect on the mutagenicity of an aminoazo dye, ortho-aminoazotoluene. Furthermore, the inhibitory effect was exerted by retinol esters such as retinol acetate and retinol palmitate, the latter being the physiological storage form of vitamin A. The inhibition is interpreted as an effect on the mixed-function oxidases that convert ortho-aminoazotoluene to its ultimate mutagenic form.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0027-5107
pubmed:author
pubmed:issnType
Print
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
225-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Retinoids as inhibitors of ortho-aminoazotoluene-induced mutagenesis in the Salmonella/liver microsome test.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't