Linked Life Data

7048947

Source:http://linkedlifedata.com/resource/pubmed/id/7048947

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-9-17
pubmed:abstractText
Macrophages from the peritoneal cavities of normal mice or mice previously immunized with epimastigotes of Trypanosoma cruzi were incubated with sera from normal or immunized mice and then infected with T. cruzi epimastigotes or trypomastigotes. After 2 hours of incubation the specimens were prepared for scanning electron microscopy. Macrophages from immunized mice were observed to be qualitatively and quantitatively more effective in binding either parasite form than were macrophages from normal mice. Preincubation with specific antibody appeared to enhance parasite binding in all cases, and extracellular destruction of both epimastigote and trypomastigote forms was noted in these preparations. While extensive destruction of epimastigotes was seen with either normal or immune macrophages pre-incubated with antibody, lysis of trypomastigotes was typically seen only in the presence of both immune macrophages and specific antibody.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9637
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
723-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Surface interactions between macrophages and Trypanosoma cruzi.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.