Linked Life Data

7048865

Source:http://linkedlifedata.com/resource/pubmed/id/7048865

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1982-9-24
pubmed:abstractText
After a brief overview of the current status of our understanding of synaptic plasticity and sprouting in the brain, sprouting in the cat red nucleus was described in detail as a model system. As the basis of our investigations of sprouting in the RN, light and electron microscopic studies, together with computer analysis of dendritic geometry by a digital image processing system, were reported. Electrophysiology using both in vivo and in vitro preparations was described; a model study using Rall's mathematical neuron model was presented. Based on these data, lesion-induced sprouting and the formation of functional synapses at an early developmental stage were investigated. This was compared with lesion-induced sprouting in adults. The synaptic transmission of synapses newly-formed by sprouting was investigated in detail. It was also reported that sprouting takes place in the absence of lesions to central neurons, in a preparation where peripheral flexor and extensor nerves were surgically crossed (cross-innervation). Finally, an attempt to correlate cortico-rubral sprouting with behavioral plasticity, using classical conditioning, was presented.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0065-227X
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
131-72
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Brain plasticity: the themes and case studies of neuro-biophysics.
pubmed:publicationType
Journal Article, Review