Linked Life Data

7047745

Source:http://linkedlifedata.com/resource/pubmed/id/7047745

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-9-24
pubmed:abstractText
This study assessed in vivo and in vitro parameters of cell-mediated immunity in 45 tuberculous meningitis patients. Delayed-type hypersensitivity responses to purified protein derivative of tuberculin (PPD), Candida albicans and streptokinase-streptodornase antigens were lacking in 34 patients compared to 2 of 54 normal volunteers. Circulating T lymphocyte subpopulations (E-rosetting active and total T cells) were diminished in 41 patients studied compared to 41 normal donors (p less than 0.001). Lymphocyte blast responses to PPD (25 micrograms-500 micrograms/ml) were positive but quantitatively depressed in all 34 patients studied compared to PPD positive normal donors (p less than 0.001). Phytohemagglutinin responses were significantly depressed (p less than 0.001). Repeat studies in 20 patients 4-5 months post-therapy resulted in reversals of all parameters to control values with heightened blastogenic responses to all PPD concentrations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0141-2760
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
37-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
In vivo and in vitro cell-mediated immunity in tuberculous meningitis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.