Linked Life Data

7043008

Source:http://linkedlifedata.com/resource/pubmed/id/7043008

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
1982-7-19
pubmed:abstractText
The influence of cimetidine hydrochloride (300 mg four times daily for seven days) on plasma ethanol concentrations and the subjective assessment of intoxication after a single oral dose of ethanol (0.8 g/kg) were investigated in a randomized double-blind placebo controlled study in six volunteers. Compared with the placebo, cimetidine produced a small increase in both the peak plasma ethanol level (from 146 +/- 5.2 to 163 +/- 7.6 mg/dL, mean +/- SEM) and th area under the ethanol concentration time curve (from 717 +/- 17 to 771 +/- 44 mg/dLXhr). In addition, using a visual analogue scale, subjects rated themselves more intoxicated at their peak of intoxication while receiving cimetidine. These results suggest that cimetidine has a small effect on the handling of ethanol in humans.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0098-7484
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
247
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2819-21
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Effects of cimetidine on the elimination and actions of ethanol.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial