Linked Life Data

7041690

Source:http://linkedlifedata.com/resource/pubmed/id/7041690

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-6-21
pubmed:abstractText
Tibiae from rats treated chronically for 12 days with enough ethanol to induce physical dependence were found to have an increased incidence of fracture during dissection and cleaning (7 of 12 or 58%) compared to control animals (1 of 12 or 8%). The site of the fractures, the proximal end of the tibia, showed an increased opacity to X-rays, and the dried bones were distinctly darker in appearance than similarly prepared control bones. The effects noted in our study suggest that the rat model could be useful for the study of the mechanisms by which alcohol affects bone growth, remodeling, and strength. These studies might shed new light on the pathogenesis of increased bone fragility in alcoholics.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0145-6008
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
96-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Evidence of a toxic effect of ethanol on bone in rats.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't