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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1982-6-24
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pubmed:abstractText |
Nasal continuous positive airway pressure (N-CPAP), applied immediately after extubation, was prospectively evaluated in 18 neonates recovering from respiratory distress syndrome. Patients were randomly assigned to N-CPAP (group 1, N=9) or a control group given oxygen by hood (group 2, N=9). Groups were comparable in birth weight and duration of intubation. In the 24-hour period following extubation, group 1 showed a significantly lower mean respiratory rate (46 +/- 2 vs 74 +/- 4), alveolar-arterial oxygen gradient (94 +/- 9 vs 134 +/- 12 mm Hg), PCO2 (45 +/- 1 vs 50 +/- 1 mm Hg), higher pH (7.33 +/- 0.01 vs 7.30 +/- 0.01), and less atelectasis by roentgenographic scores. This was associated with considerably better clinical courses in group 1 when compared with group 2, in which six patients required a late trial of N-CPAP because of respiratory deterioration and two patients needed reintubation. Postextubation N-CPAP has a striking beneficial effect on respiratory function and prevention of atelectasis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0002-922X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
359-61
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7041623-Clinical Trials as Topic,
pubmed-meshheading:7041623-Humans,
pubmed-meshheading:7041623-Infant, Newborn,
pubmed-meshheading:7041623-Intubation,
pubmed-meshheading:7041623-Positive-Pressure Respiration,
pubmed-meshheading:7041623-Prospective Studies,
pubmed-meshheading:7041623-Pulmonary Atelectasis,
pubmed-meshheading:7041623-Random Allocation,
pubmed-meshheading:7041623-Respiratory Distress Syndrome, Newborn
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pubmed:year |
1982
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pubmed:articleTitle |
Postextubation nasal continuous positive airway pressure. A prospective controlled study.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|