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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4546
|
| pubmed:dateCreated |
1982-6-24
|
| pubmed:abstractText |
Complete neonatal thymectomy reduced the frequency of spontaneous diabetes mellitus in BioBreeding/Worcester rats from 27 to 3 percent. Incomplete thymectomy also significantly reduced the frequency of diabetes (to 9 percent). These findings strengthen the hypothesis that thymus-dependent, cell-mediated autoimmune destruction of pancreatic B cells is responsible for the pathogenesis of diabetes in this experimental animal.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0036-8075
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
7
|
| pubmed:volume |
216
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
644-6
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:7041259-Animals,
pubmed-meshheading:7041259-Diabetes Mellitus, Experimental,
pubmed-meshheading:7041259-Immunity, Cellular,
pubmed-meshheading:7041259-Islets of Langerhans,
pubmed-meshheading:7041259-Rats,
pubmed-meshheading:7041259-Rats, Mutant Strains,
pubmed-meshheading:7041259-Thymectomy
|
| pubmed:year |
1982
|
| pubmed:articleTitle |
Neonatal thymectomy prevents spontaneous diabetes mellitus in the BB/W rat.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|