Linked Life Data

7039583

Source:http://linkedlifedata.com/resource/pubmed/id/7039583

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-5-27
pubmed:abstractText
Studies of clinical, audiometric and histological defects in patients with conductive otosclerosis, demonstrated the occurrence of subclinical manifestations in the hair, nails, joints and teeth. Light-microscopic examination of the skin in these patients has shown metachromasia of the ground substance and degenerative abnormalities in the collagen and elastic fibres. Structural abnormalities, in the organs developing from the ectoderm and mesoderm, led to the conclusion that otosclerosis is a universal disease characterized by ectomesodermal insufficiency, a somatic insufficiency. Optical measurement of the corneal thickness by corneometry has been introduced as an objective method for the diagnosis of somatic insufficiency. This method, now used routinely in our clinic, shows a high frequency of abnormal corneal thickness among patients with otosclerosis. Such a person is termed 'cornea-positive'. Cochlear otosclerosis with pure sensorineural hearing loss has been studied by X-ray in axial and semiaxial tomography. These patients were often X-ray positive and among them there were many cornea-positive individuals. Cases with noise-induced hearing impairment may also be cornea-positive, i.e. they may exhibit, somatic insufficiency indicating that their hearing organs are characterized by a decreased resistance to noise. Corneometry has shown its value in the diagnosis of insufficient somatic constitution typical of individuals at risk.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0020-6091
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-110
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Sensorineural hearing loss and somatic insufficiency.
pubmed:publicationType
Journal Article, Review, Case Reports