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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1982-5-21
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pubmed:abstractText |
Cis-Platinum(II)diamminodichloride (cis-PDD)-induced mutations to prototrophy were studied in Escherichia coli. Mutagenesis was not detected in a recA nor in a lexA mutant, but was greater in a uvrA strain than in a repair-proficient strain, at a given treatment of cis-PDD. Increasing the plating density above 10(5) cells per plate did not give an equivalent increase in revertants per plate [crowding depression of mutagenesis (Bockrath et al., 1980)]. Growth rates were similar at different plating densities and crowding depression of mutagenesis was observed in both excision-proficient and excision-deficient strains. A filtrate of a plate wash from crowded plates, of either treated or untreated cultures, further reduced the mutation frequencies over that due to crowding depression of mutagenesis.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0027-5107
|
pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
84
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
273-82
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7038454-Cisplatin,
pubmed-meshheading:7038454-DNA Repair,
pubmed-meshheading:7038454-Escherichia coli,
pubmed-meshheading:7038454-Mathematics,
pubmed-meshheading:7038454-Mutagens,
pubmed-meshheading:7038454-Mutation,
pubmed-meshheading:7038454-Phenotype,
pubmed-meshheading:7038454-Recombination, Genetic
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pubmed:year |
1981
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pubmed:articleTitle |
cis-Platinum(II)diamminodichloride-induced mutagenesis in E. coli K12: crowding depression of mutagenesis.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|