Linked Life Data

7035417

Source:http://linkedlifedata.com/resource/pubmed/id/7035417

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1982-4-20
pubmed:abstractText
Positive-pressure ventilation with positive end-expiratory pressure (PEEP) has been associated with elevation of left ventricular filling pressure for a stable or reduced cardiac output. To exclude the possibility that right ventricular distension due to increased pulmonary vascular resistance decreases left ventricular compliance (ventricular interdependence), we studied the effect of PEEP on left ventricular function in open-chest right-heart-bypassed dogs. A rightward shift of the left ventricular function curve was caused by 15 cmH2O PEEP without a change in the aortic pressure-flow relationship. The pericardial pressure, however, was found to exceed atmospheric pressure on 15 cmH2O even with the chest widely opened. This increase in the pressure surrounding the heart accounted for the increase in left ventricular filling pressure. We postulate, therefore, that the elevation in left ventricular filling pressure found with PEEP is due in part, if not entirely, to mechanical interaction of the heart and lungs by direct compression or pericardial traction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0161-7567
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
541-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Effect of PEEP on left ventricular function in right-heart-bypassed dogs.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't