Linked Life Data

7035319

Source:http://linkedlifedata.com/resource/pubmed/id/7035319

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1982-4-12
pubmed:abstractText
The presence of pancreatic type glucagon in the fetal and adult human gastric fundus was examined by radioimmunoassay and by an indirect immunofluorescence technique using specific antiserum against pancreatic glucagon. Although pancreatic type glucagon-containing cell (glucagon-positive cell) were demonstrated in the fetal gastric fundus in 16th, 18th, 23rd and 29th week's gestation, they were not detected in the adult gastric fundus. This immunohistochemical finding was supported by radioimmunoassay study for glucagon in gastric fundus in which there was 52 pg/mg of glucagon in the fetal gastric fundus at 20th week's gestation while glucagon was negligible in the adult gastric fundus. The findings, therefore, suggest that glucagon-positive cells in the human gastric fundus may play an important role in the maintenance of fetal life. Moreover, one fourth of glucagon-positive cells in the fetal gastric fundus reached the gut lumen with their cytoplasmic processes. In view of the finding that none of the canine glucagon-positive cells in the gastric fundus had contact with the gut lumen, the morphological feature of glucagon-positive cells in the human, fetal gastric fundus suggests that the function of glucagon-positive cells in the human, fetal gastric fundus may be somewhat different from that in other mammals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0018-5043
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
419-22
pubmed:dateRevised
2009-2-19
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Is glucagon present in the human gastric fundus?
pubmed:publicationType
Journal Article, Comparative Study