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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1982-4-12
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pubmed:abstractText |
The efficiency of mercurascan on prolongation of skin allograft survival was found to depend on the sex of experimental animals. Long-term treatment of the recipients by MSC in the mouse strain combination B10--B10.LP (donor X recipient, difference in non-H-2 loci) was more efficient in females than in males. The immunosuppressive effect of MSC was weak. MSC had no effect on the survival time of skin or heart allografts in a strain combination with limited H-2 differences [B10.D2--M(504)]. The effect of MSC on the cell membrane was followed in vitro by measurement of the rate of H-2 antigen redistribution on lymphoid cells of animals treated in vivo by MSC. The rate of redistribution on lymphoid cells from MSC-treated females was decreased; no effect was observed in the case of cells from treated males.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0015-5500
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
379-87
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7035230-Animals,
pubmed-meshheading:7035230-Dose-Response Relationship, Drug,
pubmed-meshheading:7035230-Female,
pubmed-meshheading:7035230-Fluoresceins,
pubmed-meshheading:7035230-Graft Survival,
pubmed-meshheading:7035230-H-2 Antigens,
pubmed-meshheading:7035230-Heart Transplantation,
pubmed-meshheading:7035230-Immunologic Capping,
pubmed-meshheading:7035230-Male,
pubmed-meshheading:7035230-Mice,
pubmed-meshheading:7035230-Organomercury Compounds,
pubmed-meshheading:7035230-Sex Factors,
pubmed-meshheading:7035230-Skin Transplantation,
pubmed-meshheading:7035230-Transplantation, Homologous
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pubmed:year |
1981
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pubmed:articleTitle |
Different efficiency of mercurascan in allograft survival prolongation in male and female mice.
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pubmed:publicationType |
Journal Article,
Comparative Study
|