|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1982-3-22
|
|
pubmed:abstractText |
As the initial step in the investigation of thyroid autoantibody-secreting immunocytes, we have identified such cells in vitro by the use of plaque-forming cell assays dependent on the lysis of antigen-coated sheep red blood cells. Human thyroglobulin antibody-secreting peripheral mononuclear cells were detected in six of seven patients with autoimmune thyroiditis, but not in normal control subjects. Our data indicated that 0.06-1.7% of immunoglobulin-secreting cells have the potential for human thyroglobulin antibody secretion in such patients and validated the specific plaque-forming cell technique for the investigation of thyroid autoantibody production.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0021-972X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
54
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
282-5
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1982
|
|
pubmed:articleTitle |
A specific plaque-forming cell assay for human thyroglobulin antibody-secreting immunocytes.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
