Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5835
|
pubmed:dateCreated |
1981-12-21
|
pubmed:abstractText |
Microtubule polymerization in vitro is the summation of different reactions occurring at each end of the polymer. In steady-state conditions in vitro, net tubulin addition on the microtubule occurs at one end of the polymer, and net tubulin loss occurs at the opposite end. Thus, a unidirectional flux of tubulin from one end of the microtubule to the other, or "treadmilling', can occur. The opposite end assembly--disassembly behaviour of microtubules, if it occurs within cells, could be fundamentally linked to the functions of microtubules, as, for example, in the translocation of chromosomes during mitosis.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0028-0836
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
29
|
pubmed:volume |
293
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
705-11
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7027052-Actins,
pubmed-meshheading:7027052-Animals,
pubmed-meshheading:7027052-Cattle,
pubmed-meshheading:7027052-Cell Adhesion,
pubmed-meshheading:7027052-Cell Movement,
pubmed-meshheading:7027052-Cytoskeleton,
pubmed-meshheading:7027052-Eukaryotic Cells,
pubmed-meshheading:7027052-Microtubules,
pubmed-meshheading:7027052-Mitosis,
pubmed-meshheading:7027052-Protein Binding,
pubmed-meshheading:7027052-Tubulin
|
pubmed:year |
1981
|
pubmed:articleTitle |
Microtubule treadmills--possible molecular machinery.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Review
|