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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1981-11-22
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pubmed:abstractText |
Pancreatic polypeptide (PP), 36-amino acid peptide, may function as an important feedback inhibitor of pancreatic secretion after a meal. It arises from both islet and acinar cells of the pancreas. Release of PP by a meal, primarily protein, occurs in a biphasic manner. The first rapid release occurs as a result of vagal stimulation; the second, more prolonged rise (the so-called intestinal phase) occurs in response to hormonal stimulation, predominantly cholecystokinin. Plasma PP levels increase with age; PP levels are elevated above those of age-controlled normal subjects in diabetic patients and in some patients with pancreatic amine precursor uptake decarboxylase tumors. The value of plasma PP as a possible marker for pancreatic tumors is as yet unsettled but may be a valuable tool.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0004-0010
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1256-64
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7025798-Animals,
pubmed-meshheading:7025798-Apudoma,
pubmed-meshheading:7025798-Cattle,
pubmed-meshheading:7025798-Chickens,
pubmed-meshheading:7025798-Diabetes Mellitus,
pubmed-meshheading:7025798-Dogs,
pubmed-meshheading:7025798-Humans,
pubmed-meshheading:7025798-Pancreas,
pubmed-meshheading:7025798-Pancreatic Neoplasms,
pubmed-meshheading:7025798-Pancreatic Polypeptide,
pubmed-meshheading:7025798-Sheep,
pubmed-meshheading:7025798-Swine
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pubmed:year |
1981
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pubmed:articleTitle |
Pancreatic polypeptide. A review.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|