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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1981-11-19
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pubmed:abstractText |
Physostigmine (0.25 mg-1 mg), arecoline (2 and 4 mg) and saline were administered intravenously over 30 minutes in a randomized double blind design to 11 patients with a clinical diagnosis of Alzheimer presenile dementia. Significant improvement was seen on a picture recognition test with physostigmine 0.375 mg and arecholine 4 mg. A trend towards improvement was also seen with physostigmine 0.25 mg and 0.75 mg, and arecholine 2 mg. For the majority of the patients improvement was only slight but in two patients it was clear cut and consistent.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0007-1250
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
138
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
46-50
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7023592-Alzheimer Disease,
pubmed-meshheading:7023592-Arecoline,
pubmed-meshheading:7023592-Clinical Trials as Topic,
pubmed-meshheading:7023592-Dementia,
pubmed-meshheading:7023592-Dose-Response Relationship, Drug,
pubmed-meshheading:7023592-Double-Blind Method,
pubmed-meshheading:7023592-Humans,
pubmed-meshheading:7023592-Memory,
pubmed-meshheading:7023592-Middle Aged,
pubmed-meshheading:7023592-Physostigmine
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pubmed:year |
1981
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pubmed:articleTitle |
Physostigmine and arecoline: effects of intravenous infusions in Alzheimer presenile dementia.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|