Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-11-18
pubmed:abstractText
Eighty-two per cent of tumour sections from 105 patients with lung cancer showed positive immunocytochemical localization of an anti-carcinoembryonic antigen (CEA) immunoglobulin free of antibody to normal cross-reacting antigen (NCA). The highest incidence was found in adenocarcinomas, and no association between staining and disease stage was found. There was a relationship between positive-staining tumours and preoperative and postoperative serum CEA levels of greater than or equal to 20 ng/ml, but the high incidence of CEA+, less than 20 ng/ml serum patients indicated that immunocytochemical localization was of little value in selecting patients for sequential serum monitoring. Staining for CEA was not prognostic but a preoperative serum CEA levels greater than or equal to 20 ng/ml was associated with a poor prognosis in patients undergoing radical surgery for lung cancer (P = 0.043). this prognostic effect of CEA was seen mainly in patients whose tumours showed the greatest immunocytochemical localization (P = 0.017) and in Stage III patients (P = 0.04).
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-14270243, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-202297, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-225001, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-334106, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-361204, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-4352772, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-4758660, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-5034298, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-5071695, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-5104234, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-594940, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-669747, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-69782, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-700775, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-709518, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-709519, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-7213541, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-7427084, http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-93112
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0007-0920
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-53
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Carcinoembryonic antigen and prognosis after radical surgery for lung cancer: immunocytochemical localization and serum levels.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't