rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1981-11-18
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pubmed:abstractText |
Eighty-two per cent of tumour sections from 105 patients with lung cancer showed positive immunocytochemical localization of an anti-carcinoembryonic antigen (CEA) immunoglobulin free of antibody to normal cross-reacting antigen (NCA). The highest incidence was found in adenocarcinomas, and no association between staining and disease stage was found. There was a relationship between positive-staining tumours and preoperative and postoperative serum CEA levels of greater than or equal to 20 ng/ml, but the high incidence of CEA+, less than 20 ng/ml serum patients indicated that immunocytochemical localization was of little value in selecting patients for sequential serum monitoring. Staining for CEA was not prognostic but a preoperative serum CEA levels greater than or equal to 20 ng/ml was associated with a poor prognosis in patients undergoing radical surgery for lung cancer (P = 0.043). this prognostic effect of CEA was seen mainly in patients whose tumours showed the greatest immunocytochemical localization (P = 0.017) and in Stage III patients (P = 0.04).
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-14270243,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-202297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-225001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-334106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-361204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-4352772,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-4758660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-5034298,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-5071695,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-5104234,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-594940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-669747,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-69782,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-700775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-709518,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-709519,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-7213541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-7427084,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7023523-93112
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0007-0920
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-53
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1981
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pubmed:articleTitle |
Carcinoembryonic antigen and prognosis after radical surgery for lung cancer: immunocytochemical localization and serum levels.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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