Linked Life Data

7022796

Source:http://linkedlifedata.com/resource/pubmed/id/7022796

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-10-25
pubmed:abstractText
The effect of blood transfusions on kidney graft survival in D/DR-matched host-donor combinations was investigated in rhesus monkeys treated with azathioprine and prednisolone. If host-donor combinations were mismatched for D/DR and no transfusions were given (controls), graft survival ranged from 9 to 22 days. D/DR matching alone led to survival times of 13 to 66 days with 62% of the animals showing a prolonged survival time ( greater than 22 days). However, when three pretransplant blood transfusions were given in D/DR-matched combinations, the range of graft survival was even better: 19 to 73 days with 90% of the recipients surviving for longer than 22 days. The recipients in this group also had a better kidney function in the first weeks after transplantation than that of the nontransfused D/DR-matched group. Therefore, the beneficial effects of D/DR matching and pretransplant transfusions are additive in the rhesus monkey.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0041-1337
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
48-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Pretransplant blood transfusions have an additive positive effect on kidney graft prognosis in D/DR-matched rhesus monkeys.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't