Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9 Pt 1
pubmed:dateCreated
1981-10-25
pubmed:abstractText
An in vivo transplantation technique has been developed which can be utilized to determine the reproductive survival of parenchymal hepatocytes exposed either in vitro or in vivo to both physical and chemical genotoxic agents. We have used this assay system to determine the survival of liver cells exposed to sparsely ionizing radiation. The D0 value of the survival curve was 249 rads and the extrapolation number was 1.2. These results indicate that hepatocytes irradiated while in the G0 phase are unable to accumulate sublethal damage to an appreciable extent if they are stimulated to undergo replication within 24 hr after the infliction of the damage.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0008-5472
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3512-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Transplantation system for determining the clonogenic survival of parenchymal hepatocytes exposed to ionizing radiation.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.