rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1981-9-15
|
pubmed:abstractText |
The capsular polysaccharide was isolated from Escherichia coli 010:K5:H4; it could not be obtained from a uncapsulated (K5-) mutant. It contains N-acetylglucosamine and glucuronic acid in a molar ratio of 1:1. Acid hydrolysis of the acidic polysaccharide as well as Smith degradation and degradation by deamination of the carboxyl-reduced polysaccharide suggested that the polysaccharide is composed of a disaccharide repeating unit. The data obtained by methylation analysis and nuclear magnetic resonance spectroscopy indicated that the repeating sequence of the capsular polysaccharide is the 4-beta-glucuronyl-1,4-alpha-N-acetylglucosaminyl unit. This structure is similar to that of desulfo-heparin.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0014-2956
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
116
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
359-64
|
pubmed:dateRevised |
2007-7-23
|
pubmed:meshHeading |
pubmed-meshheading:7018909-Acetylation,
pubmed-meshheading:7018909-Antigens,
pubmed-meshheading:7018909-Antigens, Bacterial,
pubmed-meshheading:7018909-Antigens, Surface,
pubmed-meshheading:7018909-Carbohydrate Sequence,
pubmed-meshheading:7018909-Carbohydrates,
pubmed-meshheading:7018909-Escherichia coli,
pubmed-meshheading:7018909-Humans,
pubmed-meshheading:7018909-Magnetic Resonance Spectroscopy,
pubmed-meshheading:7018909-Mass Spectrometry,
pubmed-meshheading:7018909-Methylation,
pubmed-meshheading:7018909-Urinary Tract Infections
|
pubmed:year |
1981
|
pubmed:articleTitle |
The structure of the capsular polysaccharide (K5 antigen) of urinary-tract-infective Escherichia coli 010:K5:H4. A polymer similar to desulfo-heparin.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|