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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1981-8-10
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pubmed:abstractText |
The ontogeny of the rat supraoptic (SON) and paraventricular (PVN) nuclei was studied using a combined fluorescence-immunocytochemical technique for the simultaneous localization of catecholamines (CA) and neurophysin (NP). NP neurons and CA varicosities were first detected in the SON and PVN at 1 days postcoitus. The development of NP neurons which included increases in immunoreactivity in both nuclei proceeded through fetal and neonatal stages, approaching maturity by 21-28 days postnatal; the maturation of the PVN lagged behind that of the SON. CA varicosities appear to make contact with NP neurons beginning at 21-22 days postnatal adult-like patterns were established. The prenatal dominance of NP stain relative to CA fluorescence may suggest a possible neurotrophic role for magnocellular neurons and/or their products upon ingrowing noradrenergic axons.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0196-9781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
77-95
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7017621-Aging,
pubmed-meshheading:7017621-Animals,
pubmed-meshheading:7017621-Catecholamines,
pubmed-meshheading:7017621-Female,
pubmed-meshheading:7017621-Fetus,
pubmed-meshheading:7017621-Fluorescent Antibody Technique,
pubmed-meshheading:7017621-Hypothalamus,
pubmed-meshheading:7017621-Neurons,
pubmed-meshheading:7017621-Neurophysins,
pubmed-meshheading:7017621-Paraventricular Hypothalamic Nucleus,
pubmed-meshheading:7017621-Pregnancy,
pubmed-meshheading:7017621-Rats,
pubmed-meshheading:7017621-Supraoptic Nucleus
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pubmed:year |
1980
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pubmed:articleTitle |
Simultaneous monoamine histofluorescence and neuropeptide immunocytochemistry: III. Ontogeny of catecholamine varicosities and neurophysin neurons in the rat supraoptic and paraventricular nuclei.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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