Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1981-8-10
|
| pubmed:abstractText |
Blood from full-term newborns was compared to adult blood for its ability to regenerate prostaglandin I2 (PGI2)-like activity from vascular tissue. The neonate possesses a markedly decreased ability to regenerate PGI2 (0.10 4/- 0.07 ng/mg vascular tissue) when compared to the adult (0.42 +/- 0.12). This decreased activity was not due to the presence of an inhibitor in neonatal blood. The impaired ability of neonatal blood to regenerate PGI2-like activity was related to its markedly decreased antioxidant potential and was corrected (0.34 +/- 0.08 ng/mg vascular tissue) by the addition of Vitamin E in vitro. Plasma PGI2-like regenerating activity had normalized by 3 to 5 months of age (0.41 +/- 0.11 ng/mg).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0031-3998
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
971-3
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1981
|
| pubmed:articleTitle |
Deficiency of plasma PGI2-like regenerating activity in neonatal plasma. Reversal by vitamin E in vitro.
|
| pubmed:publicationType |
Journal Article,
In Vitro
|