Linked Life Data

7015482

Source:http://linkedlifedata.com/resource/pubmed/id/7015482

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-7-20
pubmed:abstractText
We have performed serial fine-needle aspiration biopsies from human allografts undergoing acute rejection episodes. After subtraction of blood background, the method enables a numerical evaluation of the composition of the inflammatory infiltrate. In all rejections, T lymphoblasts and especially B plasmablasts were prominent at the beginning, whereafter the blast cell response subsided. If only traces of other inflammatory cell types were seen in the aspirates, the rejections were clinically mild usually lasting less than 5 days. If the blast response was accompanied by a considerable influx of lymphocytes but only few mononuclear phagocytes, the clinical course was intermediately intensive, although these rejections were usually reversible. If, however, the blast cells and lymphocytes were accompanied by large numbers of monocytes, and if the maturation of blood-borne monocytes into tissue macrophages was evident, the rejections were severe and usually irreversible. Thus the appearance of large numbers of macrophages in the aspirates is a bad prognostic sign, indicating an unfavourable course and irreversible rejection.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0300-9475
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-97
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Monitoring of human renal allograft rejection with fine-needle aspiration cytology.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't